Mammographic Breast Density and Family History of Breast Cancer

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Family history, mammographic density, and risk of breast cancer.

PURPOSE Mammographic density is a strong and highly heritable risk factor for breast cancer. The purpose of this study was to examine the extent to which mammographic density explains the association of family history of breast cancer with risk of the disease. SUBJECTS AND METHODS We carried out three nested case-control studies in screening programs that included in total 2,322 subjects (1,1...

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Mammographic breast density, endocrine therapies, and breast cancer risk

MBD and breast cancer risk Elevated MBD is considered one of the strongest risk factors for breast cancer regardless of whether it is assessed as a categorical or quantitative measure.6 Women in the highest categories of breast density have a 4to 6-fold increased breast cancer risk compared with women in the lowest categories. MBD has been shown to be a stronger risk factor for breast cancer th...

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Association of diet and mammographic breast density in the Minnesota breast cancer family cohort.

Mammographic breast density is a significant risk factor for breast cancer. The present report analyzes the association of breast density and dietary factors in 1508 women in a historical cohort study of breast cancer families in Minnesota. Diet was assessed by a semiquantitative food frequency questionnaire. Percent breast density was estimated visually by a radiologist experienced in mammogra...

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Association between mammographic breast density and breast cancer tumor characteristics.

OBJECTIVE Few studies have examined the association between breast density and breast cancer tumor characteristics. We examined the association between hormonal, proliferative, and histologic tumor characteristics and mammographic breast density in women with breast cancer. METHODS We conducted a cross-sectional analysis in 546 women diagnosed with invasive breast cancer to evaluate the assoc...

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Investigating the Factors Affecting the Mammographic Density of Breast Tissue in Patients Referred to the Breast Cancer Research Center, Iran

Introduction: Of the factors leading to false negative results in mammography is breast tissue density, and by increasing the density of breast tissue in mammography, the mammography sensitivity decreases. On the other hand, increasing the breast tissue density leads to increased risk of breast cancer. Various factors such as inheritance, genetics, hormonal and reproductive factors, and nutriti...

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ژورنال

عنوان ژورنال: JNCI Journal of the National Cancer Institute

سال: 2003

ISSN: 0027-8874,1460-2105

DOI: 10.1093/jnci/95.7.556